Best answer
ShortnSnappy
Short answer: Nope. It's one ENB or the highway in Fallout 4. Mixing them up is asking for a graphics apocalypse.
All answers
VaultDwellerJess
Tried it once, thinking maybe I could get the best of both worlds. Nope, my game turned into a slideshow even my grandma wouldn't sit through. One ENB is the golden rule.
TechieGamer101
Nah, you can't use multiple ENBs at the same time in Fallout 4. ENBs are like those fancy dress costumes - one at a time. If you try to load up more than one, they'll clash and cause all sorts of graphical glitches or even crashes. Stick to one and tweak it till it's just right!