How Did Itachi Die in Naruto Shippuden?
Itachi died during his final battle with Sasuke. He succumbed to his illness and the injuries sustained in the fight.
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Itachi died while fighting Sasuke, he was sick and overexerted himself.
Itachi's death was a result of his terminal illness, but he chose to die at Sasuke's hands to help his brother grow stronger.
He fought Sasuke and then he died because he was already super sick. End of story.
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