How do you kill Progenitus in MTG?
Just play "Terminus". It puts all creatures on the bottom of their owners' libraries. Doesn't target, doesn't deal damage, Progenitus is just swept away in the cleaning.
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In my experience, the best way to handle Progenitus is to not let it hit the battlefield at all. Use counter spells or discard effects to keep it out of play. Prevention is better than cure!
Honestly, just ignore it. Build your deck to win through other means than direct combat. If Progenitus can't hit you, it can't win by itself.
Oh boy, Progenitus is a tough cookie with that "protection from everything" shield! But fret not, there are a few sly ways around it. One method is using cards that don't target or deal damage but change the rules of the game, like "Sudden Spoiling" which can turn it into a 0/2 with no abilities, ripe for squashing. Another clever trick is to force your opponent to sacrifice it, with cards like "Plaguecrafter". Just because you can't target or damage it, doesn't mean you can't make it vanish!
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